PODXL anticorps

N° du produit ABIN1589722

Cet anticorps Souris Monoclonal détecte spécifiquement PODXL dans IF et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour PODXL anticorps (ABIN1589722)

Antigène: PODXL (Podocalyxin-Like (PODXL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PODXL est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GB6D9

Détail du produit anti-PODXL anticorps

Specificité: Membrane protein fraction of isolated human glomeruli

Attributs du produit: Chromosomal location: 7q32-q33
Monoclonal antibodies were produced with the help of BALB/c mice using a membrane protein fraction of isolated human glomeruli as the immunizing antigen.

Purification: The mouse IgG1 antibody (#4D5aE5E6) from hybridomas was purified from cell culture supernatant by Protein G chromatography.

Isotype: IgG1

Information d'application

Indications d'application: IF/IHC: use at 2-5 µg/mL.

Commentaires:

Monoclonal Antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Conseil sur la manipulation: Centrifuge vial prior to opening.

Stock: -20 °C

Stockage commentaire: The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.

Date de péremption: 6 months

Détails sur PODXL

Antigène: PODXL (Podocalyxin-Like (PODXL))

Autre désignation: Podocalyxin

Sujet: Podocalyxin is the major sialoprotein in the glycocalyx of glomerular podocytes. It was shown that endothelial cell membranes contain Podocalyxin. By immunoelectron microscopy Podocalyxin was localized on the luminal membrane domain of endothelial cells, in a patchy distribution. The presence of Podocalyxin was confirmed in SDS extracts of lung tissue by immunoblotting. It is concluded that (a) Podocalyxin is a widespread component of endothelial plasma membranes, (b) it is restricted to the luminal membrane domain, and (c) it is distributed unevenly on the endothelial cell surface.
Synonyms: PODXL, PC, PCLP, Gp200, PCLP-1, Podocalyxin-like protein, GCTM-2 antigen, Gp200

NCBI Accession: NM_001018111, NP_001018121

UniProt: O00592

Pathways: Tube Formation